KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
17.58
Human Site:
S453
Identified Species:
35.15
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
S453
N
M
E
N
A
V
G
S
L
Y
V
R
E
A
F
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
S455
N
M
E
N
A
V
G
S
L
Y
V
R
E
A
F
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
R425
N
M
E
N
A
V
G
R
L
Y
V
E
A
A
F
Dog
Lupus familis
XP_546737
807
92419
S481
N
M
E
S
A
V
G
S
L
Y
V
R
E
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
S439
N
M
E
S
A
V
G
S
L
Y
I
K
R
A
F
Rat
Rattus norvegicus
P0C1T0
774
89178
S448
N
M
E
S
A
V
G
S
L
Y
I
K
R
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
A423
N
M
E
N
A
V
G
A
M
Y
V
R
E
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
A429
N
M
E
N
A
V
G
A
L
Y
V
R
E
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
A526
K
L
G
V
A
V
G
A
L
F
I
R
D
N
F
Honey Bee
Apis mellifera
XP_392502
776
89056
A453
K
L
G
M
A
V
G
A
L
F
I
R
D
N
F
Nematode Worm
Caenorhab. elegans
O16796
848
97043
A523
V
L
P
L
A
A
G
A
I
Y
V
Q
A
H
F
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
K441
A
M
D
F
A
T
G
K
M
Y
V
K
E
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
80
93.3
N.A.
73.3
73.3
N.A.
N.A.
80
N.A.
86.6
N.A.
40
40
33.3
46.6
P-Site Similarity:
100
100
80
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
93.3
N.A.
73.3
73.3
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
100
9
0
42
0
0
0
0
17
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
17
0
0
% D
% Glu:
0
0
67
0
0
0
0
0
0
0
0
9
50
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
100
% F
% Gly:
0
0
17
0
0
0
100
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
34
0
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
9
0
0
0
25
0
0
0
% K
% Leu:
0
25
0
9
0
0
0
0
75
0
0
0
0
0
0
% L
% Met:
0
75
0
9
0
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
67
0
0
42
0
0
0
0
0
0
0
0
0
25
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
59
17
0
0
% R
% Ser:
0
0
0
25
0
0
0
42
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
0
% T
% Val:
9
0
0
9
0
84
0
0
0
0
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _